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Search Results for " coagulation factor xi "

Targets Recommended: Factor Xa

1

抑制剂 & 化合物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T79847	Frunexian EP-7041	Factor Xa	Metabolism
	Frunexian (EP-7041) 为针对 Factor XIa 的选择性有效凝血因子 XI/活化因子 XI 抑制剂，展现抗血栓活性，且在大鼠肠系膜动脉穿刺模型中显示出无出血倾向。此化合物亦可应用于体外膜氧合(ECMO)的研究领域。

化合物

Cat.No: T79847

Synonym: EP-7041

Target: Factor Xa

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01104	Coagulation factor XI/F11 Protein, Human, Recombinant (His) coagulation factor 11,coagulation...	Human	HEK293 Cells
	Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the presence of calcium ions. It is an unusual dimeric protease, with structural features that distinguish it from vitamin K-dependent coagulation proteases. The factor XI is synthesized in the liver as a single polypeptide chain with a molecular weight estimated between 125 ~160 kDa ...
TMPK-01271	Coagulation factor XI Protein, Cynomolgus, Recombinant (His) F11,PTA,FXI,Coagulation factor	Cynomolgus	HEK293 Cells
	Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).
TMPH-03268	Coagulation factor XI Protein, Rat, Recombinant (His & Myc) Coagulation factor XI,F11	Rat	E. coli
	Coagulation factor XI Protein, Rat, Recombinant (His & Myc) is expressed in E. coli.
TMPH-03106	Coagulation factor XII Protein, Pig, Recombinant (His) HAF,Hageman factor,F12,Coagulation fac...	Sus scrofa (Pig)	E. coli
	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. Coagulation factor XII Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predic...
TMPJ-00734	KNG1 Protein, Human, Recombinant (His) KNG1,High Molecular Weight Kininogen,BDK,HMWK,KNG,Williams-F...	Human	HEK293 Cells
	Kininogen-1 is a secreted protein which contains three cystatin domains. There are two alternatively spliced forms, designated as the high molecular weight (HMW) and low MW (LMW) forms. Kininogen-1 plays a critical role in blood coagulation and inflammatory response. Kininogens are inhibitors of thiol proteases. Kininogen-1 participates in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII, also inhibits the thrombin- and plasmin-induced aggregation...
TMPH-02832	Serpin A5 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin comple...

重组蛋白

Coagulation factor XI/F11 Protein, Human, Recombinant (His)

Cat.No: TMPY-01104

Species: Human

Expression System: HEK293 Cells

Coagulation factor XI Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01271

Species: Cynomolgus

Expression System: HEK293 Cells

Coagulation factor XI Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03268

Species: Rat

Expression System: E. coli

Coagulation factor XII Protein, Pig, Recombinant (His)

Cat.No: TMPH-03106

Species: Sus scrofa (Pig)

Expression System: E. coli

KNG1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00734

Species: Human

Expression System: HEK293 Cells

Serpin A5 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02832

Species: Mouse

Expression System: Baculovirus Insect Cells

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